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p-Chlorophenyl sulfone

Bis(4-chlorophenyl) sulphone

CAS: 80-07-9

Molecular Formula: C12H8Cl2O2S

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p-Chlorophenyl sulfone - Names and Identifiers

Name Bis(4-chlorophenyl) sulphone
Synonyms p-chlorophenyl sulfone
p-Chlorophenyl sulfone
di-p-chlorophenylsulfone
4,4'-dichlorophenyl sulfone
4,4'-Dichlorophenyl sulfone
bis(p-chlorophenyl) sulfone
p,p'-dichlorodiphenylsulfone
Bis(4-chlorophenyl) sulphone
4,4'-dichlorodiphenyl sulfone
4,4-Dichloro Diphenyl Sulfone
p,p'-Dichlorodiphenyl sulfone
4,4'-Dichloro Biphenyl Sulfone
4,4[-Dichlorodiphenyl sulphone
4,4'-Dichloro Diphenyl Sulfone
4,4'-Dichloro Diphenyl Sulphone
1,1'-sulfonylbis(4-chlorobenzene)
1,1'-sulfonylbis[4-chloro-benzene]
Benzene, 1,1'-sulfonylbis[4-chloro-
Benzene, 1,1'-sulfonylbis*4-chloro-
4-chloro-1-(4-chlorophenylsulfonyl)benzene
CAS 80-07-9
EINECS 201-247-9
InChI InChI=1/C12H8Cl2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H

p-Chlorophenyl sulfone - Physico-chemical Properties

Molecular FormulaC12H8Cl2O2S
Molar Mass287.16
Density1.54g/cm3
Melting Point143-146°C(lit.)
Boling Point250°C10mm Hg(lit.)
Flash Point233 °C
Water Solubility<0.1 g/100 mL at 20 ºC
Solubility Dichloromethane
Vapor Presure0Pa at 25℃
AppearanceWhite to white-like powder
ColorWhite
BRN2052955
Storage ConditionSealed in dry,Room Temperature
StabilityStable. Combustible. Incompatible with strong oxidizing agents.
SensitiveMoisture Sensitive
Refractive Index1.61
MDLMFCD00000619
Physical and Chemical PropertiesWhite monoclinic crystals.
UseUsed for Engineering Plastics polysulfone raw materials, also used as pharmaceutical, auxiliary intermediates

p-Chlorophenyl sulfone - Risk and Safety

Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S37/39 - Wear suitable gloves and eye/face protection
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany2
RTECSWR3450000
TSCAYes
HS Code29309070
Hazard NoteHarmful/Corrosive/Moisture Sensitive
ToxicityLD50 orl-mus: 24 g/kg HCACAV 29,1317,46

p-Chlorophenyl sulfone - Nature

Open Data Verified Data

white monoclinic crystals. The melting point was 148-149 °c. Boiling point sublimation. Density 1.54g/cm3. Insoluble in water, slightly soluble in cold ethanol.

Last Update：2025-06-10 22:55:16

p-Chlorophenyl sulfone - Preparation Method

Open Data Verified Data
  • The chlorosulfonic acid method uses chlorobenzene to react with chlorosulfonic acid to obtain 4 chlorobenzene sulfonyl chloride, and then condenses with chlorobenzene in the presence of aluminum trichloride to obtain the finished product after refining.
  • sulfuric acid method to industrial sulfuric acid, chlorobenzene as raw materials, using batch method or continuous synthesis of this product, the reaction is carried out in the presence of excess chlorobenzene.
Last Update：2022-01-01 10:56:13

p-Chlorophenyl sulfone - Application

Open Data Verified Data

The main intermediate of engineering plastics polysulfone, is also the treatment of leprosy drugs 4, 4r_amino two phenyl sulfone raw materials.

Last Update：2025-08-19 16:24:40

p-Chlorophenyl sulfone - Safety

Open Data Verified Data
  • low toxicity, the use of chlorobenzene in the production process is toxic substances, the skin, eyes, nose and respiratory system has a strong irritation. Chlorosulfonic acid toxicity and irritation is more intense. Therefore, the production process must pay attention to the tightness of the equipment, to prevent leakage. Good ventilation should be maintained at the production site, and the operator should wear protective equipment.
  • It is packed in an iron drum lined with plastic bags, 35kg per barrel. Store in a dry, ventilated place to avoid sun exposure and prevent heat and moisture. According to the general provisions of the storage and transportation of chemicals.
Last Update：2025-06-10 22:55:16

p-Chlorophenyl sulfone - Reference Information

LogP3.9 at 20℃
NIST chemical information information provided by: webbook.nist.gov (external link)
EPA chemical substance information information provided by: ofmpeb.epa.gov (external link)
Use used in the synthesis of engineering plastics, dyes and polymers, such as polysulfone, polyethersulfone, polyetheretherketone, etc.
used as a raw material of engineering plastics polysulfone, also used in the production of 4,4 '-diaminodiphenyl sulfone
used as a raw material of engineering plastics polysulfone, also used in medicine, intermediate of the adjuvant
production method 1. Chlorosulfonic acid method with chlorobenzene and chlorosulfonic acid reaction of 4-chlorobenzenesulfonyl chloride, and chlorobenzene in the presence of aluminum chloride condensation, refined products. Sulfuric acid method to industrial sulfuric acid, chlorobenzene as raw materials, using batch method or continuous synthesis of this product, the reaction is carried out in the presence of excess chlorobenzene.
category toxic substances
toxicity grade low toxicity
Acute toxicity oral-rat LD50: >20000 mg/kg; Oral-mouse LD50: 24000 mg/kg
flammability hazard characteristics flammability; Toxic sulfur oxide and chloride fumes from combustion
storage and transportation characteristics warehouse ventilation and low temperature drying
fire extinguishing agent dry powder, foam, sand, carbon dioxide, water mist
toxic substance data information provided by: pubchem.ncbi.nlm.nih.gov (external link)
Last Update：2024-04-09 15:16:52
p-Chlorophenyl sulfone
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Shanghai Yuanye Bio-Technology Co., Ltd.
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CAS: 80-07-9
Tel: 18301782025
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Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Bis(4-chlorophenyl) Sulfone Visit Supplier Webpage Request for quotation
CAS: 80-07-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Jiangsu Pules Biotechnology Co.,Ltd.
Spot supply
Product Name: Bis(4-chlorophenyl) sulphone Request for quotation
CAS: 80-07-9
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
JIANGSU BSECHEM CHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Bis(4-chlorophenyl) sulphone Request for quotation
CAS: 80-07-9
Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
QQ: 3787852685 Click to send a QQ message
Wechat: chemical6666
Nantong Reform Petro-Chemical CO., LTD.
Spot supply
Product Name: Bis(4-chlorophenyl) sulphone Request for quotation
CAS: 80-07-9
Tel: +86-13776910623
Email: r@reformchem.com­
Mobile: +86-13776910623
QQ: 3785839865 Click to send a QQ messageSend QQ message
Wechat: chemical6666 
Guangzhou Yuanda New Material Co.,Ltd
Product Name: 4,4'-Dichlorodiphenyl sulfone Request for quotation
CAS: 80-07-9
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589 Click to send a QQ message
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: 4,4'-Sulfonylbis(chlorobenzene) Request for quotation
CAS: 80-07-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
Changsha Changtang import and Export Co., Ltd.
Product Name: 4,4 '-Dichlorodiphenyl sulfone Request for quotation
CAS: 80-07-9
Tel: +86 18942506900
Email: lilyqu@chemoway.com
Mobile: +86 18942506900
QQ: 3182628472 Click to send a QQ message
Wechat: +86 18942506900
WhatsApp: +86 18942506900
Linkedin: +86 18942506900
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: 4,4-Dichlorodiphenyl sulfone Visit Supplier Webpage Request for quotation
CAS: 80-07-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: Bis(4-chlorophenyl) sulphone Request for quotation
CAS: 80-07-9
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Shanghai Yuanye Bio-Technology Co., Ltd.
Multiple SpecificationsSpot supply
Product Name: Bis(4-Chlorophenyl) Sulfone Visit Supplier Webpage Request for quotation
CAS: 80-07-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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p-Chlorophenyl sulfone
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